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1

In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb

Oihana Murillo, Juan Dubrot, Asís Palazón, Ainhoa Arina, Arantza Azpilikueta, Carlos Alfaro, Sarai Solano, María C. Ochoa, Carmen Berasain, Izaskun Gabari, José. L. Pérez-Gracia, Pedro Berraondo, Sand

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 532 KB

english, 2009

2

Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-α

Ana Rouzaut, Saray Garasa, Álvaro Teijeira, Iranzu González, Ivan Martinez-Forero, Natalia Suarez, Esther Larrea, Carlos Alfaro, Asís Palazón, Juan Dubrot, Sandra Hervás-Stubbs, Ignacio Melero

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 578 KB

english, 2010

3

Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8+ T cells

Sandra Hervas-Stubbs, Jose-Ignacio Riezu-Boj, Iranzu Gonzalez, Uxua Mancheño, Juan Dubrot, Arantza Azpilicueta, Izaskun Gabari, Asis Palazon, Alicia Aranguren, Juan Ruiz, Jesus Prieto, Esther Larrea,

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 888 KB

english, 2010

4

Intratumoral injection of interferon-α and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy

Juan Dubrot, Asis Palazón, Carlos Alfaro, Arantza Azpilikueta, María Carmen Ochoa, Ana Rouzaut, Iván Martinez-Forero, Alvaro Teijeira, Pedro Berraondo, Agnes Le Bon, Sandra Hervás-Stubbs, Ignacio Mele

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.61 MB

english, 2011

5

Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo

Natalia Suarez, Carlos Alfaro, Juan Dubrot, Asis Palazon, Elixabet Bolaños, Lorena Erro, Sandra Hervas-Stubbs, Ivan Martinez-Forero, Aizea Morales-Kastresana, Salvador Martin-Algarra, Bruno Sangro, Fe

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

6

Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ

Juan Dubrot, Francisca Milheiro, Carlos Alfaro, Asis Palazón, Ivan Martinez-Forero, Jose L. Perez-Gracia, Aizea Morales-Kastresana, José L. Romero-Trevejo, María C. Ochoa, Sandra Hervás-Stubbs, Jesús

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 888 KB

english, 2010

7

Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells

Juan Dubrot, Aitziber Portero, Gorka Orive, Rosa María Hernández, Asis Palazón, Ana Rouzaut, Jose L. Perez-Gracia, Sandra Hervás-Stubbs, Jose Luis Pedraz, Ignacio Melero

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 900 KB

english, 2010

8

International symposium on CTL and immunostimulation, Pamplona (Spain), October 26th and 27th 2010

Maria C. Ochoa, Sandra Hervas-Stubbs, Asis Palazon, Ivan Martinez-Forero, Pedro Berraondo, Pablo Sarobe, Alan Melcher, Ignacio Melero

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 177 KB

english, 2011

9

Surfing the waves of the tide model of T cell co-stimulation

Elena Marín-Díez, Iván Martínez-Forero, Ignacio Melero, Asís Palazón

Journal:

Year:

2012

Language:

english

File:

PDF, 464 KB

english, 2012

10

Polly Matzinger's “danger model” finds its predicted danger-denoting self moieties

Asis Palazón, Juan Dubrot, Iván Martinez-Forero, Ana Rouzaut-Subirá, Carmen Ochoa, José Luis Perez-Gracia, Sandra Hervás-Stubbs, Ignacio Melero

Journal:

Year:

2008

File:

PDF, 93 KB

2008

11

Interferon producing killer dendritic cells (IKDC): A matter of controversy

Aizea Morales, Carmen Ochoa, Asís Palazón, Juan Dubrot, Belén Palencia, Carlos Alfaro, Natalia Suarez, Iván Martínez Forero, Sandra Hervás-Stubbs, Ignacio Melero

Journal:

Year:

2010

File:

PDF, 97 KB

2010

12

SimB16: Modeling Induced Immune System Response against B16-Melanoma

Pappalardo, Francesco, Forero, Ivan Martinez, Pennisi, Marzio, Palazon, Asis, Melero, Ignacio, Motta, Santo, Brusic, Vladimir

Journal:

Year:

2011

Language:

english

File:

PDF, 816 KB

english, 2011

13

HIF Transcription Factors, Inflammation, and Immunity

Palazon, Asis, Goldrath, Ananda W., Nizet, Victor, Johnson, Randall S.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

14

Immune Response Regulation in the Tumor Microenvironment by Hypoxia

Labiano, Sara, Palazon, Asis, Melero, Ignacio

Journal:

Seminars in Oncology

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

15

Intensive Pharmacological Immunosuppression Allows for Repetitive Liver Gene Transfer With Recombinant Adenovirus in Nonhuman Primates

Fontanellas, Antonio, Hervás-Stubbs, Sandra, Mauleón, Itsaso, Dubrot, Juan, Mancheño, Uxua, Collantes, María, Sampedro, Ana, Unzu, Carmen, Alfaro, Carlos, Palazón, Asis, Smerdou, Cristian, Benito, Alb

Journal:

Molecular Therapy

Year:

2010

File:

PDF, 1.15 MB

2010

16

Intensive Pharmacological Immunosuppression Allows for Repetitive Liver Gene Transfer With Recombinant Adenovirus in Nonhuman Primates

Fontanellas, Antonio, Hervás-Stubbs, Sandra, Mauleón, Itsaso, Dubrot, Juan, Mancheño, Uxua, Collantes, María, Sampedro, Ana, Unzu, Carmen, Alfaro, Carlos, Palazón, Asis, Smerdou, Cristian, Benito, Alb

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

17

Cardiotrophin-1 determines liver engraftment of syngenic colon carcinoma cells through an immune system-mediated mechanism

Bustos, Matilde, Dubrot, Juan, Martinez-Anso, Eduardo, Larequi, Eduardo, Castaño, David, Palazon, Asis, Belza, Idoia, Sanmamed, Miguel F., Perez-Gracia, Jose Luis, Ortiz de Solorzano, Carlos, alfaro,

Journal:

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

18

Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism

Labiano, Sara, Palazón, Asis, Bolaños, Elixabet, Azpilikueta, Arantza, R. Sánchez-Paulete, Alfonso, Morales-Kastresana, Aizea, Quetglas, Jose I., Perez-Gracia, José L., Gúrpide, Alfonso, Rodriguez-Rui

Journal:

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

19

S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate

Tyrakis, Petros A., Palazon, Asis, Macias, David, Lee, Kian. L., Phan, Anthony. T., Veliça, Pedro, You, Jia, Chia, Grace S., Sim, Jingwei, Doedens, Andrew, Abelanet, Alice, Evans, Colin E., Griffiths,

Journal:

Year:

2016

Language:

english

File:

PDF, 4.26 MB

english, 2016

20

Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection

Phan, Anthony T., Doedens, Andrew L., Palazon, Asis, Tyrakis, Petros A., Cheung, Kitty P., Johnson, Randall S., Goldrath, Ananda W.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.85 MB

english, 2016

21

CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes

Labiano, Sara, Meléndez-Rodríguez, Florinda, Palazón, Asís, Teijeira, Álvaro, Garasa, Saray, Etxeberria, Iñaki, Aznar, M. Ángela, Sánchez-Paulete, Alfonso R., Azpilikueta, Arantza, Bolaños, Elixabet,

Journal:

Year:

2017

Language:

english

File:

PDF, 3.27 MB

english, 2017

22

Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis

Evans, Colin E., Palazon, Asis, Sim, Jingwei, Tyrakis, Petros A., Prodger, Alice, Lu, Xiao, Chan, Saria, Bendahl, Pär-Ola, Belting, Mattias, Von Euler, Love, Rundqvist, Helene, Johnson, Randall S., Br

Journal:

Year:

2017

Language:

english

File:

PDF, 16.85 MB

english, 2017

23

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

Palazon, Asis, Tyrakis, Petros A., Macias, David, Veliça, Pedro, Rundqvist, Helene, Fitzpatrick, Susan, Vojnovic, Nikola, Phan, Anthony T., Loman, Niklas, Hedenfalk, Ingrid, Hatschek, Thomas, Lövrot,

Journal:

Year:

2017

Language:

english

File:

PDF, 3.67 MB

english, 2017

24

The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia

Sim, Jingwei, Cowburn, Andrew S., Palazon, Asis, Madhu, Basetti, Tyrakis, Petros A., Macías, David, Bargiela, David M., Pietsch, Sandra, Gralla, Michael, Evans, Colin E., Kittipassorn, Thaksaon, Chey,

Journal:

Cell Metabolism

Year:

2018

Language:

english

File:

PDF, 4.04 MB

english, 2018

25

Carcinoma-Derived Interleukin-8 Disorients Dendritic Cell Migration Without Impairing T-Cell Stimulation

Alfaro, Carlos, Suárez, Natalia, Martínez-Forero, Ivan, Palazón, Asís, Rouzaut, Ana, Solano, Sarai, Feijoo, Esperanza, Gúrpide, Alfonso, Bolaños, Elixabet, Erro, Lorena, Dubrot, Juan, Hervás-Stubbs, S

Journal:

Year:

2011

Language:

english

File:

PDF, 977 KB

english, 2011

26

Dendritic Cells Take up and Present Antigens from Viable and Apoptotic Polymorphonuclear Leukocytes

Alfaro, Carlos, Suarez, Natalia, Oñate, Carmen, Perez-Gracia, Jose L., Martinez-Forero, Ivan, Hervas-Stubbs, Sandra, Rodriguez, Inmaculada, Perez, Guiomar, Bolaños, Elixabet, Palazon, Asis, de Sanmame

Journal:

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

27

A cell-engineered system to assess tumor cell sensitivity to CD8 + T cell-mediated cytotoxicity

Nelson, Nadine, Lopez-Pelaez, Marta, Palazon, Asis, Poon, Edmund, De La Roche, Maike, Barry, Simon, Valge-Archer, Viia, Wilkinson, Robert W., Dovedi, Simon J., Smith, Paul D.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.64 MB

english, 2019

28

Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment

Prieto-FernÃ¡ndez, Endika, Egia-Mendikute, Leire, Bosch, Alexandre, GarcÃa del RÃo, Ana, Jimenez-Lasheras, Borja, AntoÃ±ana-Vildosola, Asier, Lee, So Young, Palazon, Asis

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 6.32 MB

2020